Ontology highlight
ABSTRACT:
SUBMITTER: Kanemaru H
PROVIDER: S-EPMC5584452 | biostudies-literature | 2017 Aug
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20170814 35
The development of effective treatments against cancers is urgently needed, and the accumulation of CD8<sup>+</sup> T cells within tumors is especially important for cancer prognosis. Although their mechanisms are still largely unknown, growing evidence has indicated that innate immune cells have important effects on cancer progression through the production of various cytokines. Here, we found that <i>basic leucine zipper transcription factor ATF-like 2</i> (<i>Batf2</i>) has an antitumor effec ...[more]