Increased risk of influenza among vaccinated adults who are obese.

ABSTRACT:

Background

Influenza infects 5-15% of the global population each year, and obesity has been shown to be an independent risk factor for increased influenza-related complications including hospitalization and death. However, the risk of developing influenza or influenza-like illness (ILI) in a vaccinated obese adult population has not been addressed.

Objective

This study evaluated whether obesity was associated with increased risk of influenza and ILI among vaccinated adults.

Subjects and methods

During the 2013-2014 and 2014-2015 influenza seasons, we recruited 1042 subjects to a prospective observational study of trivalent inactivated influenza vaccine (IIV3) in adults. A total of 1022 subjects completed the study. Assessments of relative risk for laboratory confirmed

SUBMITTER: Neidich SD 

PROVIDER: S-EPMC5585026 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature