Aging-related changes in the diversity of women's skin microbiomes associated with oral bacteria.

ABSTRACT: Skin aging is associated with changes in cutaneous physiology including interactions with a skin microbial community. A striking alteration and diversification in the skin microbiome with aging was observed between two different age groups of 37 healthy Japanese women, i.e. younger adults of 21-37 years old and older adults of 60-76 years old, using bacterial 16S rRNA gene sequencing. The analyses revealed that the alpha diversity/species richness was significantly higher in the older than the younger group for the cheek and forehead microbiomes, while the beta diversity in the overall structure significantly differed particularly for the forearm and scalp microbiomes between the two age groups. Taxonomic profiling showed a striking reduction in the relative abundance of the majority skin

SUBMITTER: Shibagaki N 

PROVIDER: S-EPMC5585242 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature