A new red cell index and portable RBC analyzer for screening of iron deficiency and Thalassemia minor in a Chinese population.

ABSTRACT: Anemia is a widespread public health problem with 1/4 ~1/3 of the world's population being affected. In Southeast Asia, Thalassemia trait (TT) and iron deficiency anemia (IDA) are the two most common anemia types and can have a serious impact on quality of life. IDA patients can be treated with iron supplementation, yet TT patients have diminished capacity to process iron. Therefore, distinguishing between types of anemia is essential for effective diagnosis and treatment. Here, we present two advances towards low-cost screening for anemia. First: a new red-cell-based index, Joint Indicator A, to discriminate between IDA, TT, and healthy children in a Chinese population. We collected retrospective data from 384 Chinese children and used discriminant function analysis to determine the best

SUBMITTER: Tong L 

PROVIDER: S-EPMC5585383 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature