Essential Role of the Cytoplasmic Chemoreceptor TlpT in the De Novo Formation of Chemosensory Complexes in Rhodobacter sphaeroides.

ABSTRACT: Bacterial chemosensory proteins form large hexagonal arrays. Several key features of chemotactic signaling depend on these large arrays, namely, cooperativity between receptors, sensitivity, integration of different signals, and adaptation. The best-studied arrays are the membrane-associated arrays found in most bacteria. Rhodobacter sphaeroides has two spatially distinct chemosensory arrays, one is transmembrane and the other is cytoplasmic. These two arrays work together to control a single flagellum. Deletion of one of the soluble chemoreceptors, TlpT, results in the loss of the formation of the cytoplasmic array. Here, we show the expression of TlpT in a tlpT deletion background results in the reformation of the cytoplasmic array. The number of arrays formed is dependent on the cell le

SUBMITTER: Jones CW 

PROVIDER: S-EPMC5585706 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature