The Recombination Landscape in Wild House Mice Inferred Using Population Genomic Data.

ABSTRACT: Characterizing variation in the rate of recombination across the genome is important for understanding several evolutionary processes. Previous analysis of the recombination landscape in laboratory mice has revealed that the different subspecies have different suites of recombination hotspots. It is unknown, however, whether hotspots identified in laboratory strains reflect the hotspot diversity of natural populations or whether broad-scale variation in the rate of recombination is conserved between subspecies. In this study, we constructed fine-scale recombination rate maps for a natural population of the Eastern house mouse, Mus musculus castaneus We performed simulations to assess the accuracy of recombination rate inference in the presence of phase errors, and we used a novel ap

SUBMITTER: Booker TR 

PROVIDER: S-EPMC5586380 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature