Persistent Hyperglycemia Is Associated With Increased Mortality After Intracerebral Hemorrhage.

ABSTRACT:

Background

Hyperglycemia may be associated with worse outcome after intracerebral hemorrhage (ICH). We assessed the association of early glycemic trajectory on ICH mortality and edema growth.

Methods and results

We included patients from the Helsinki ICH study with glucose measurements at least once between both 0 to 24 and 24 to 72 hours from onset. Hyperglycemia was defined as blood glucose ≥8 mmol/L (144 mg/dL) based on the local threshold for treatment. Glycemic trajectory was defined on maximum values 0 to 24 and 24 to 72 hours after ICH: (1) persistent normoglycemia in both epochs; (2) late hyperglycemia (only between 24 and 72 hours); (3) early hyperglycemia (only before 24 hours); and (4) persistent hyperglycemia in both epochs. Logistic regression with known predict

SUBMITTER: Wu TY 

PROVIDER: S-EPMC5586431 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature