Parental age and childhood cancer risk: A Danish population-based registry study.

ABSTRACT:

Background

Though the association between parental age at child's birth and the risk of childhood cancer has been previously investigated, the evidence to date is inconclusive and scarce for rarer cancer types.

Methods

Cancer cases (N=5,856) were selected from all children born from 1968 to 2014 and diagnosed from 1968 to 2015 in Denmark at less than 16 years of age listed in the nationwide Danish Cancer Registry. Cases were individually matched to controls (1:100) on sex and year of birth with a total of 585,594 controls randomly sampled from all live births in Denmark from the Danish Central Population Registry. Parental age at child's birth was extracted from the Central Population Registry. Conditional logistic regression models were used to estimate odds ratios for the

SUBMITTER: Contreras ZA 

PROVIDER: S-EPMC5586505 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature