Is cardiovascular risk reduction therapy effective in South Asian, Chinese and other patients with diabetes? A population-based cohort study from Canada.

ABSTRACT:

Objectives

Guidelines recommend ACE inhibitors (ACEi), angiotensin receptor blockers (ARBs), calcium channel blockers (CCBs) and diuretics in all patients with diabetes mellitus. However, the effectiveness of these agents in South Asian and Chinese populations is unknown. We sought to determine whether ACEi, ARB, CCB and diuretics are associated with reduced mortality in South Asian, Chinese and other patients with diabetes.

Design

Population-based cohort study using administrative health databases.

Setting

Province of British Columbia, Canada (2006-2013).

Participants

Patients aged ≥35 years with incident diabetes.

Primary and secondary outcome measures

Primary outcome was all-cause mortality for each medication class compared with untreated patients wi

SUBMITTER: Ke CH 

PROVIDER: S-EPMC5588972 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature