Prevalence and clinical characteristics of apparent therapy-resistant hypertension in patients with cardiovascular disease: a cross-sectional cohort study in secondary care.

ABSTRACT:

Objectives

Our aim was to investigate the prevalence of apparent therapy-resistant hypertension (aTRH) in patients with clinical manifest cardiovascular disease (CVD), and to study clinical characteristics related to aTRH in this population.

Setting

The SMART (Second Manifestations of ARTerial disease) study is a large, single-centre cohort study in secondary care.

Participants

Office blood pressure (BP) at inclusion was used to evaluate BP control in 6191 hypertensive patients with clinical manifest (cardio)vascular disease. Therapy-resistant hypertension was defined as BP ≥140/90 mm Hg despite use of antihypertensive drugs from ≥3 drug classes including a diuretic or use of ≥4 antihypertensive drugs irrespective of BP. Logistic regression analysis was used to explor

SUBMITTER: de Beus E 

PROVIDER: S-EPMC5589036 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature