Patterns of Oxygen Pulse Curve in Response to Incremental Exercise in Patients with Chronic Obstructive Pulmonary Disease - An Observational Study.

ABSTRACT: In COPD, pulmonary hyperinflation causes decreased stroke volume thereby decreased oxygen pulse (O₂P). While O₂P flattening is related to myocardial ischemia in cardiac patients, O₂P patterns have seldom been explored in COPD. The aims of the study were to investigate O₂P-curve patterns and associated factors in COPD. Seventy-five patients with stable COPD were enrolled. The demographics, cardiac size, physiological measurements and stress EKG were compared among O₂P-curve pattern groups. An algorithm to identify O₂P-curve patterns was developed in 28 patients. In the remaining 45 patients after excluding two with poor effort, this algorithm revealed 20 (44%) flattening, 16 (36%) increasing, and nine (20%) decreasing pattern

SUBMITTER: Chuang ML 

PROVIDER: S-EPMC5589739 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature