Assessment of the interaction of age and sex on 90-day outcome after intracerebral hemorrhage.

ABSTRACT:

Objective

Because age affects hormonal production differently in women compared with men, we sought to define sex and age interactions across a multiracial/ethnic population after intracerebral hemorrhage (ICH) to uncover evidence that loss of gonadal hormone production would result in loss of the known neuroprotective effects of gonadal hormones.

Methods

Clinical and radiographic data from participants in the Ethnic/Racial Variations of Intracerebral Hemorrhage study and the Genetic and Environmental Risk Factors for Hemorrhagic Stroke study prior to December 2013 were used. Relationships among sex, age, and outcome after ICH in 616 non-Hispanic black, 590 Hispanic, and 868 non-Hispanic white participants were evaluated using multivariable logistic regression analysis. Poor

SUBMITTER: James ML 

PROVIDER: S-EPMC5589792 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature