Mass Azithromycin and Malaria Parasitemia in Niger: Results from a Community-Randomized Trial.

ABSTRACT: Studies designed to determine the effects of mass administration of azithromycin on trachoma have suggested that mass azithromycin distributions may also reduce the prevalence of malaria. These studies have typically examined the impact of a small number of treatments over short durations. In this prespecified substudy of a cluster-randomized trial for trachoma, we compared malaria parasitemia prevalence in 24 communities in Niger randomized to receive either annual or biannual mass azithromycin distributions over 3 years. The 12 communities randomized to annual azithromycin received three treatments during the high-transmission season, and the 12 communities randomized to biannual azithromycin received a total of six treatments: three during the high-transmission season and three during t

SUBMITTER: O'Brien KS 

PROVIDER: S-EPMC5590561 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature