Perceived stress and telomere length: A systematic review, meta-analysis, and methodologic considerations for advancing the field.

ABSTRACT:

Importance

Psychological stress contributes to numerous diseases and may do so in part through damage to telomeres, protective non-coding segments on the ends of chromosomes.

Objective

We conducted a systematic review and meta-analysis to determine the association between self-reported, perceived psychological stress (PS) and telomere length (TL).

Data sources

We searched 3 databases (PubMed, PsycInfo, and Scopus), completed manual searches of published and unpublished studies, and contacted all study authors to obtain potentially relevant data.

Study selection

Two independent reviewers assessed studies for original research measuring (but not necessarily reporting the correlation between) PS and TL in human subjects. 23 studies met inclusion criteria; 22 (tota

SUBMITTER: Mathur MB 

PROVIDER: S-EPMC5590630 | biostudies-literature | 2016 May

REPOSITORIES: biostudies-literature