Mycoplasma pneumoniae and health outcomes in children with asthma.

ABSTRACT:

Background

Acute infections with Mycoplasma pneumoniae (Mp) have been associated with worsening asthma in children. Mp can be present in the respiratory tract for extended periods; it is unknown whether the long-term persistence of Mp in the respiratory tract affects long-term asthma control.

Objective

To determine the effect of Mp on asthma control.

Methods

We enrolled 31 pediatric subjects 3 to 10 years of age with persistent asthma who completed up to 8 visits over a 24-month period. We detected Mp by antigen capture and polymerase chain reaction. Primary outcome measurements included symptom scores, quality of life, medication scores, oral corticosteroid use, health care usage, school absences, and exhaled breath condensate pH.

Results

Low levels of Mp comm

SUBMITTER: Wood PR 

PROVIDER: S-EPMC5590634 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature