Clinical features and seasonality of parechovirus infection in an Asian subtropical city, Hong Kong.

ABSTRACT:

Background

The epidemiology of human parechovirus (HPeV) in Asia remains obscure. We elucidated the prevalence, seasonality, type distribution and clinical presentation of HPeV among children in Hong Kong.

Methods

A 24-month prospective study to detect HPeV in children ≤36 months hospitalized for acute viral illnesses.

Results

2.3% of the 3911 children examined had HPeV infection, with most (87.5%) concentrated in September-January (autumn-winter). 81.3% were HPeV1 and 12.5% were HPeV4, while HPeV3 was rare (2.5%). HPeV was a probable cause of the disease in 47.7% (42/88), mostly self-limiting including acute gastroenteritis, upper respiratory tract infection and maculopapular rash. A neonate developed severe sepsis-like illness with HPeV3 as the only pathogen detecte

SUBMITTER: Chiang GPK 

PROVIDER: S-EPMC5590978 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature