Body Fat Distribution and the Risk of Incident Metabolic Syndrome: A Longitudinal Cohort Study.

ABSTRACT: The effect of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) area on metabolic syndrome (MS) has been debated. We aimed to evaluate the effects of VAT and SAT on the incidence of MS and its components in a large and apparently healthy Asian population. We performed a longitudinal cohort study of 1,964 subjects who received health screenings over a 5-year follow-up period; 317 incidents of MS (16.1%) were observed during a median follow-up of 4.5 years. The VAT area was significantly associated with a higher incidence of MS; the adjusted HR for incident MS per 1 SD of VAT was 1.50 (95% CI 1.29-1.74), and the adjusted HR of the 5^th VAT quintile compared with the 1^st quintile was 3.73 (95% CI 2.22-6.28). However, the SAT area was not associated with

SUBMITTER: Kwon H 

PROVIDER: S-EPMC5591218 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature