Electroencephalography Network Effects of Corpus Callosotomy in Patients with Lennox-Gastaut Syndrome.

ABSTRACT:

Objectives

This study aimed to investigate the functional network effects of corpus callosotomy (CC), a well-recognized palliative surgical therapy for patients with Lennox-Gastaut syndrome (LGS). Specifically, we sought to gain insight into the effects of CC on LGS remission, based on brain networks in LGS by calculating network metrics and evaluating by network measures before and after surgery.

Methods

Electroencephalographic recordings made during preoperative and 3-month postoperative states in 14 patients with LGS who had undergone successful CC were retrospectively analyzed. First, undirected correlation matrices were constituted for the mathematical expression of functional networks. Then, we plotted these networks to analyze the effects of CC on connectivity. In add

SUBMITTER: Liang JG 

PROVIDER: S-EPMC5591410 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature