Association of Clinical Reactivity with Sensitization to Allergen Components in Multifood-Allergic Children.

ABSTRACT:

Background

Thirty percent of children with food allergies have multiple simultaneous allergies; however, the features of these multiple allergies are not well characterized serologically or clinically.

Objective

We comprehensively evaluated 60 multifood-allergic patients by measuring serum IgE to key allergen components, evaluating clinical histories and medication use, performing skin tests, and conducting double-blind, placebo-controlled food challenges (DBPCFCs).

Methods

Sixty participants with multiple food allergies were characterized by clinical history, DBPCFCs, total IgE, specific IgE, and component-resolved diagnostics (IgE and IgG4) data. The food allergens tested were almond, egg, milk, sesame, peanut, pecan, walnut, hazelnut, cashew, pistachio, soy, and wh

SUBMITTER: Andorf S 

PROVIDER: S-EPMC5592131 | biostudies-literature | 2017 Sep - Oct

REPOSITORIES: biostudies-literature