Prognostic value of miliary versus non-miliary sub-staging in advanced ovarian cancer.

ABSTRACT:

Objective

The presence of miliary disease during initial ovarian cancer debulking may reflect a distinct mode of peritoneal spread independent from size-based tumor staging and may explain variation in response to treatment and survival outcomes. To infer the prevalence, presentation and clinical implications of miliary disease we reviewed existing surgical records.

Methods

Reports were available for 1008 primary debulking surgeries for ovarian, primary peritoneal or fallopian tube cancer between 2001 and 2015 (685 reports from 2005 to 2015). Clinical outcome data was available for 938 patients. We analyzed a high-stage sub-cohort for survival (N=436).

Results

Most records were evaluable for miliary disease (761/938); for these, the miliary phenotype was highly preval

SUBMITTER: Eng KH 

PROVIDER: S-EPMC5592637 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature