Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats.

ABSTRACT: Sex differences in the expression of social behavior are typically apparent in adolescent and adult rats. While the neurobiology underlying juvenile social play behavior has been well characterized, less is known about discrete brain regions involved in adult responsiveness to a same sex peer. Furthermore, whether adult males and females differ in their responsiveness to a social interaction in terms of neuronal activation indexed via immediate early gene (IEG) expression remains to be determined. Thus, the present study was designed to identify key sites relevant to the processing of sensory stimuli (generally) or social stimuli (specifically) after brief exposure to a same-sex social partner by assessing IEG expression. Four-month-old male and female Fisher (F) 344 rats (N=38; n=5-8/grou

SUBMITTER: Perkins AE 

PROVIDER: S-EPMC5592796 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature