Infections by human gastrointestinal helminths are associated with changes in faecal microbiota diversity and composition.

ABSTRACT: Investigations of the impact that patent infections by soil-transmitted gastrointestinal nematode parasites exert on the composition of the host gut commensal flora are attracting growing interest by the scientific community. However, information collected to date varies across experiments, and further studies are needed to identify consistent relationships between parasites and commensal microbial species. Here, we explore the qualitative and quantitative differences between the microbial community profiles of cohorts of human volunteers from Sri Lanka with patent infection by one or more parasitic nematode species (H+), as well as that of uninfected subjects (H-) and of volunteers who had been subjected to regular prophylactic anthelmintic treatment (Ht). High-throughput sequencing of th

SUBMITTER: Jenkins TP 

PROVIDER: S-EPMC5593201 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature