Antidepressant use during pregnancy and psychiatric disorders in offspring: Danish nationwide register based cohort study.

ABSTRACT: Objective To investigate the association between in utero exposure to antidepressants and risk of psychiatric disorders.Design Population based cohort study.Setting Danish national registers.Participants 905 383 liveborn singletons born during 1998-2012 in Denmark and followed from birth until July 2014, death, emigration, or date of first psychiatric diagnosis, whichever came first. The children were followed for a maximum of 16.5 years and contributed 8.1×10⁶ person years at risk.Exposures for observational studies Children were categorised into four groups according to maternal antidepressant use within two years before and during pregnancy: unexposed, antidepressant discontinuation (use before but not during pregnancy), antidepressant conti

SUBMITTER: Liu X 

PROVIDER: S-EPMC5594425 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature