The dynamic landscape of gene regulation during Bombyx mori oogenesis.

ABSTRACT:

Background

Oogenesis in the domestic silkworm (Bombyx mori) is a complex process involving previtellogenesis, vitellogenesis and choriogenesis. During this process, follicles show drastic morphological and physiological changes. However, the genome-wide regulatory profiles of gene expression during oogenesis remain to be determined.

Results

In this study, we obtained time-series transcriptome data and used these data to reveal the dynamic landscape of gene regulation during oogenesis. A total of 1932 genes were identified to be differentially expressed among different stages, most of which occurred during the transition from late vitellogenesis to early choriogenesis. Using weighted gene co-expression network analysis, we identified six stage-specific gene modules that corre

SUBMITTER: Zhang Q 

PROVIDER: S-EPMC5594438 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature