Neuroimmune expression in hip osteoarthritis: a systematic review.

ABSTRACT:

Background

Neuroimmune axis is central in the physiopathology of hip osteoarthritis (OA), but its specific pathways are still unclear. This systematic review aims to assess the nervous and immune system profile of patients with hip osteoarthritis (OA) when compared to healthy controls.

Methods

A systematic review followed PRISMA guidelines was conducted. A two-step selection process was completed, and from 609 references 17 were included. The inclusion criteria were: original articles on adult patients with hip OA, with assessment of neuroimmune expression. Articles with other interventions prior to analysis and those without a control group were excluded.

Results

Thirty-nine relevant neuroimmune markers were identified, with assessments in bone, cartilage, synovial m

SUBMITTER: da Silva MR 

PROVIDER: S-EPMC5594449 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature