Phylogenomics of Colombian Helicobacter pylori isolates.

ABSTRACT:

Background

During the Spanish colonisation of South America, African slaves and Europeans arrived in the continent with their corresponding load of pathogens, including Helicobacter pylori. Colombian strains have been clustered with the hpEurope population and with the hspWestAfrica subpopulation in multilocus sequence typing (MLST) studies. However, ancestry studies have revealed the presence of population components specific to H. pylori in Colombia. The aim of this study was to perform a thorough phylogenomic analysis to describe the evolution of the Colombian urban H. pylori isolates.

Results

A total of 115 genomes of H. pylori were sequenced with Illumina technology from H. pylori isolates obtained in Colombia in a region of high risk

SUBMITTER: Gutierrez-Escobar AJ 

PROVIDER: S-EPMC5594506 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature