Evidence-based practice within nutrition: what are the barriers for improving the evidence and how can they be dealt with?

ABSTRACT:

Background

Evidence-based clinical research poses special barriers in the field of nutrition. The present review summarises the main barriers to research in the field of nutrition that are not common to all randomised clinical trials or trials on rare diseases and highlights opportunities for improvements.

Methods

Systematic academic literature searches and internal European Clinical Research Infrastructure Network (ECRIN) communications during face-to-face meetings and telephone conferences from 2013 to 2017 within the context of the ECRIN Integrating Activity (ECRIN-IA) project.

Results

Many nutrients occur in multiple forms that differ in biological activity, and several factors can alter their bioavailability which raises barriers to their assessment. These includ

SUBMITTER: Laville M 

PROVIDER: S-EPMC5594518 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature