An intra-neural microstimulation system for ultra-high field magnetic resonance imaging and magnetoencephalography.

ABSTRACT:

Background

Intra-neural microstimulation (INMS) is a technique that allows the precise delivery of low-current electrical pulses into human peripheral nerves. Single unit INMS can be used to stimulate individual afferent nerve fibres during microneurography. Combining this with neuroimaging allows the unique monitoring of central nervous system activation in response to unitary, controlled tactile input, with functional magnetic resonance imaging (fMRI) providing exquisite spatial localisation of brain activity and magnetoencephalography (MEG) high temporal resolution.

New method

INMS systems suitable for use within electrophysiology laboratories have been available for many years. We describe an INMS system specifically designed to provide compatibility with both ultra-high

SUBMITTER: Glover PM 

PROVIDER: S-EPMC5594527 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature