Predicted networks of protein-protein interactions in Stegodyphus mimosarum by cross-species comparisons.

ABSTRACT:

Background

Stegodyphus mimosarum is a candidate model organism belonging to the class Arachnida in the phylum Arthropoda. Studies on the biology of S. mimosarum over the past several decades have consisted of behavioral research and comparison of gene sequences based on the assembled genome sequence. Given the lack of systematic protein analyses and the rich source of information in the genome, we predicted the relationships of proteins in S. mimosarum by bioinformatics comparison with genome-wide proteins from select model organisms using gene mapping.

Results

The protein-protein interactions (PPIs) of 11 organisms were integrated from four databases (BioGrid, InAct, MINT, and DIP). Here, we present comprehensive prediction and analysis of 3810 proteins in S. mimosarum with

SUBMITTER: Wang X 

PROVIDER: S-EPMC5594591 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature