Effects of cerebral near-infrared spectroscopy on the outcome of patients undergoing cardiac surgery: a systematic review of randomised trials.

ABSTRACT:

Objectives

Goal-directed optimisation of cerebral oxygenation using near-infrared spectroscopy (NIRS) during cardiopulmonary bypass is widely used. We tested the hypotheses that the use of NIRS cerebral oximetry results in reductions in cerebral injury (neurocognitive function, serum biomarkers), injury to other organs including the heart and brain, transfusion rates, mortality and resource use.

Design

Systematic review and meta-analysis.

Setting

Tertiary cardiac surgery centres in North America, Europe and Asia.

Participants

A search of Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, Medline, Embase, and the Cumulative Index to Nursing and Allied Health Literature Plus from inception to November 2016 identified 10 randomised trials, enrolli

SUBMITTER: Serraino GF 

PROVIDER: S-EPMC5595187 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature