A catalog of Xenopus tropicalis transcription factors and their regional expression in the early gastrula stage embryo.

ABSTRACT: Gene regulatory networks (GRNs) involve highly combinatorial interactions between transcription factors and short sequence motifs in cis-regulatory modules of target genes to control cellular phenotypes. The GRNs specifying most cell types are largely unknown and are the subject of wide interest. A catalog of transcription factors is a valuable tool toward obtaining a deeper understanding of the role of these critical effectors in any biological setting. Here we present a comprehensive catalog of the transcription factors for the diploid frog Xenopus tropicalis. We identify 1235 genes encoding DNA-binding transcription factors, comparable to the numbers found in typical mammalian species. In detail, the repertoire of X. tropicalis transcription factor genes is nearly identical to human and

SUBMITTER: Blitz IL 

PROVIDER: S-EPMC5596316 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature