A checklist is associated with increased quality of reporting preclinical biomedical research: A systematic review.

ABSTRACT: Irreproducibility of preclinical biomedical research has gained recent attention. It is suggested that requiring authors to complete a checklist at the time of manuscript submission would improve the quality and transparency of scientific reporting, and ultimately enhance reproducibility. Whether a checklist enhances quality and transparency in reporting preclinical animal studies, however, has not been empirically studied. Here we searched two highly cited life science journals, one that requires a checklist at submission (Nature) and one that does not (Cell), to identify in vivo animal studies. After screening 943 articles, a total of 80 articles were identified in 2013 (pre-checklist) and 2015 (post-checklist), and included for the detailed evaluation of reporting methodological and ana

SUBMITTER: Han S 

PROVIDER: S-EPMC5597130 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature