Neurosyphilis in Africa: A systematic review.

ABSTRACT:

Introduction

Neurological involvement is one of the most important clinical manifestations of syphilis and neurological disease occurs in both early and late syphilis. The impact of HIV co-infection on clinical neurosyphilis remains unclear. The highest prevalence of both syphilis and HIV is in Africa. Therefore it might be expected that neurosyphilis would be an important and not uncommon manifestation of syphilis in Africa and frequently occur in association with HIV co-infection; yet few data are available on neurosyphilis in Africa. The aim of this study is to review data on neurosyphilis in Africa since the onset of the HIV epidemic.

Methods

We searched the literature for references on neurosyphilis in Africa for studies published between the 1st of January 1990 and 15t

SUBMITTER: Marks M 

PROVIDER: S-EPMC5597251 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature