Background controlled QTL mapping in pure-line genetic populations derived from four-way crosses.

ABSTRACT: Pure lines derived from multiple parents are becoming more important because of the increased genetic diversity, the possibility to conduct replicated phenotyping trials in multiple environments and potentially high mapping resolution of quantitative trait loci (QTL). In this study, we proposed a new mapping method for QTL detection in pure-line populations derived from four-way crosses, which is able to control the background genetic variation through a two-stage mapping strategy. First, orthogonal variables were created for each marker and used in an inclusive linear model, so as to completely absorb the genetic variation in the mapping population. Second, inclusive composite interval mapping approach was implemented for one-dimensional scanning, during which the inclusive linear model w

SUBMITTER: Zhang S 

PROVIDER: S-EPMC5597784 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature