Biphasic cuirass ventilation is better than bag-valve mask ventilation for resuscitation following organophosphate poisoning.

ABSTRACT:

Objective

Exposure to organophosphates (OP) may lead to a life threatening cholinergic crisis with death attributed to a rapidly progressive respiratory failure. In a toxicological mass casualty event involving organophosphate exposure, many of the victims may depend on immediate short-term ventilation to overcome the respiratory distress which may exhaust life supporting resources. In addition, the mandatory use of personal protective gear by first responders emphasizes the need for a noninvasive, easy-to-operate ventilation device. Our objective was to assess the efficacy of MRTX, a Biphasic Cuirass Ventilation device, in comparison with standard bag-valve mask ventilation following acute organophosphate poisoning.

Methods

Pigs were exposed to paraoxon poisoning (1.4 LD

SUBMITTER: Gur I 

PROVIDER: S-EPMC5598215 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature