Evaluation of mutagenic and antimicrobial properties of brown propolis essential oil from the Brazilian Cerrado biome.

ABSTRACT: Biological, and particularly antimicrobial, activities have been demonstrated for the essential oil of propolis samples worlwide, yet their mutagenic effects remain unknown. To correlate antimicrobial effects with mutagenic risks, the present study evaluated the antifungal and antibacterial activities of the essential oil obtained from brown propolis collected from the Cerrado biome in Midwest Brazil (EOP), testing it against nine pathogenic microorganisms. Evaluation of mutagenic potential was based on the somatic mutation and recombination test (SMART) performed on wing cells of standard (ST) and high-bioactivation (HB) crosses of Drosophila melanogaster. EOP was extracted by hydrodistillation, and sesquiterpenes were characterized by GC⿿MS as its major constituents. The crude oil

SUBMITTER: Fernandes FH 

PROVIDER: S-EPMC5598219 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature