Phenotypic and familial associations between childhood maltreatment and cannabis initiation and problems in young adult European-American and African-American women.

ABSTRACT:

Background

Childhood maltreatment is a known risk factor for cannabis initiation and problem use, but the extent to which this association is attributable to shared familial influences is unknown. We estimate the magnitude of associations between childhood maltreatment, timing of cannabis initiation, and cannabis-related problems, in European-American (EA) and African-American (AA) women, and parse the relative influence of additive genetic (A), shared environmental (C), and individual-specific environmental (E) factors on these constructs and their covariation.

Methods

Data were from diagnostic telephone interviews conducted with 3786 participants (14.6% AA) in a population-based study of female twins. Logistic regression analyses and twin modeling were used to test for ass

SUBMITTER: Grant JD 

PROVIDER: S-EPMC5599374 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature