Slow-release praziquantel for dogs: presentation of a new formulation for echinococcosis control.

ABSTRACT:

Background

Echinococcosis is a serious, zoonotic, parasitic disease with worldwide distribution. According to a epidemiological survey in 2012 in China, there are 20,000 infected patients and more than 50 million people at the risk. As the dog is the main, definitive host, the Government of China encourages monthly praziquantel treatment of every dog. However, this is difficult to achieve in geographically challenging areas, such as the Tibetan plateau, where there are also many dogs without owners. To overcome these problems, we investigated the transmission blocking capacity of a slow-release formulation of praziquantel administered by subcutaneous injection.

Methods

The impact of a slow-release preparation of two pharmacokinetically stereoselective praziquantel enantiomer

SUBMITTER: Jiang B 

PROVIDER: S-EPMC5599885 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature