Biological characterization of fenpicoxamid, a new fungicide with utility in cereals and other crops.

ABSTRACT:

Background

The development of novel highly efficacious fungicides that lack cross-resistance is extremely desirable. Fenpicoxamid (Inatreq™ active) possesses these characteristics and is a member of a novel picolinamide class of fungicides derived from the antifungal natural product UK-2A.

Results

Fenpicoxamid strongly inhibited in vitro growth of several ascomycete fungi, including Zymoseptoria tritici (EC₅₀ , 0.051 mg L^-1 ). Fenpicoxamid is converted by Z. tritici to UK-2A, a 15-fold stronger inhibitor of Z. tritici growth (EC₅₀ , 0.0033 mg L^-1 ). Strong fungicidal activity of fenpicoxamid against driver cereal diseases was confirmed in greenhouse tests, where activity on Z. tritici and Puccinia triticina matched that of fluxapyr

SUBMITTER: Owen WJ 

PROVIDER: S-EPMC5599960 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature