Impact on survival of warfarin in patients with pulmonary arterial hypertension receiving subcutaneous treprostinil.

ABSTRACT:

Introduction

Anticoagulation is a common treatment modality in patients with pulmonary arterial hypertension (PAH). Further studies are needed to appropriately assess the risk/benefit ratio of anticoagulation, particularly in PAH patients receiving PAH-specific therapies.

Aims

We use observational long-term data on PAH patients treated with subcutaneous (SQ) treprostinil from a large open-label study. Patients were followed for up to 4 years. The use of warfarin and bleeding events were recorded.

Results

At total of 860 patients (age [mean±SD] 46±15 years, 76% female, 83% Caucasian, 49% idiopathic PAH, and 76% New York Heart Association [NYHA] functional class III) were included. All patients received SQ treprostinil (15% also other pulmonary hypertension [PH]-therapi

SUBMITTER: Ascha M 

PROVIDER: S-EPMC5600501 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature