Cardiovascular Pharmacogenomics and Cognitive Function in Patients with Schizophrenia.

ABSTRACT: The authors sought to examine the impact of multiple risk alleles for cognitive dysfunction and cardiovascular disease risk on cognitive function and to determine if these relationships varied by cognitive reserve (CR) or concomitant medication use in patients with schizophrenia. They conducted a cross-sectional study in ambulatory mental health centers. A total of 122 adults with a schizophrenia spectrum diagnosis who were maintained on a stable antipsychotic regimen for at least 6 months before study enrollment were included. Patients were divided into three CR groups based on years of formal education: no high school completion or equivalent (low-education group [18 patients]), completion of high school or equivalent (moderate-education group [36 patients], or any degree of post-high sc

SUBMITTER: Ward KM 

PROVIDER: S-EPMC5600660 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature