Effect of androgen deprivation therapy on intraprostatic tumour volume identified on ¹⁸F choline PET/CT for prostate dose painting radiotherapy.

ABSTRACT:

Objective

Prostate dose painting radiotherapy requires the accurate identification of dominant intraprostatic lesions (DILs) to be used as boost volumes; these can be identified on multiparametric MRI (mpMRI) or choline positron emission tomography (PET)/CT. Planning scans are usually performed after 2-3 months of androgen deprivation therapy (ADT). We examine the effect of ADT on choline tracer uptake and boost volumes identified on choline PET/CT.

Methods

Fluoroethylcholine (¹⁸F choline) PET/CT was performed for dose painting radiotherapy planning in patients with intermediate- to high-risk prostate cancer. Initially, they were performed at planning. Owing to low visual tracer uptake, PET/CT for subsequent patients was performed at staging. We compared these two

SUBMITTER: Chan J 

PROVIDER: S-EPMC5601534 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature