Segmental arterial stiffness in relation to B-type natriuretic peptide with preserved systolic heart function.

ABSTRACT:

Background

Central arterial stiffness has been shown to play a key role in cardiovascular disease. However, evidence regarding such arterial stiffness from various arterial segments in relation to B-type natriuretic peptide (BNP) remains elusive.

Methods

A total of 1255 participants (47.8% men; mean age: 62.6 ± 12.3 [SD] years) with preserved left ventricular function (ejection fraction ≥50%) and ≥1 risk factors were consecutively studied. Arterial pulse wave velocity (PWV) by automatic device (VP-2000; Omron Healthcare) for heart-femoral (hf-PWV), brachial-ankle (ba-PWV), and heart-carotid (hc-PWV) segments were obtained and related to BNP concentrations (Abbott Diagnostics, Abbott Park, IL, USA).

Results

Subjects in the highest hf-PWV quartile were older and had wor

SUBMITTER: Yen CH 

PROVIDER: S-EPMC5602521 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature