Failure of outpatient antibiotics among patients hospitalized for acute bacterial skin infections: What is the clinical relevance?

ABSTRACT:

Background

Infectious Diseases Society of America guidelines recommend that patients hospitalized for acute bacterial skin infections after failure of outpatient antibiotic therapy be managed as "severe" infections; however, the clinical relevance of apparent failure of outpatient therapy is not clear.

Methods

This was a secondary analysis of a multicenter, retrospective cohort of adults and children hospitalized for cellulitis, abscess, or wound infection. We compared clinical features, laboratory and microbiology findings, antibiotic treatment, and outcomes among patients who received outpatient antibiotics prior to admission and those who did not.

Results

Of 533 patients, 179 (34%) received outpatient antibiotics prior to admission. Compared with those who did not,

SUBMITTER: Jenkins TC 

PROVIDER: S-EPMC5602597 | biostudies-literature | 2016 Jun

REPOSITORIES: biostudies-literature