The (FTO) gene polymorphism is associated with metabolic syndrome risk in Egyptian females: a case- control study.

ABSTRACT:

Background

Variations within fat mass and obesity associated (FTO) gene had crosstalk with obesity risk in European and some Asian populations. This study was designed to investigate FTO rs9939609 association with metabolic syndrome (MetS) as well as biochemical parameters as plasma glucose, serum triacylglycerol (TAG), total cholesterol (TC) and transaminases enzymes in Arab female population from Egypt.

Methods

In order to achieve that, FTO gene rs9939609 (A < T) was genotyped using TaqMan SNP Genotyping Assay in a total of 197 females which were enrolled in this study. Fasting levels of serum insulin, lipid profile and plasma glucose, in addition to liver transaminases were measured. The association between the genotype distribution and MetS risk was evaluated using Chi-s

SUBMITTER: Khella MS 

PROVIDER: S-EPMC5603034 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature