The impact of BMI on non-malignant respiratory symptoms and lung function in arsenic exposed adults of Northern Chile.

ABSTRACT:

Background

Elevated body mass index (BMI) and arsenic are both associated with cancer and with non-malignant lung disease. Using a unique exposure situation in Northern Chile with data on lifetime arsenic exposure, we previously identified the first evidence of an interaction between arsenic and BMI for the development of lung cancer.

Objectives

We examined whether there was an interaction between arsenic and BMI for the development of non-malignant lung disease.

Methods

Data on lifetime arsenic exposure, respiratory symptoms, spirometry, BMI, and smoking were collected from 751 participants from cities in Northern Chile with varying levels of arsenic water concentrations. Spirometry values and respiratory symptoms were compared across subjects in different categories

SUBMITTER: Nardone A 

PROVIDER: S-EPMC5603214 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature