A Cumulative Deficit Laboratory Test-based Frailty Index: Personal and Neighborhood Associations.

ABSTRACT:

Objectives

To explore the association between a newly developed cumulative laboratory-based frailty index (FI) and intrinsic (personal) and extrinsic (social, environmental) characteristics.

Design

Cross-sectional longitudinal study.

Setting

The third and fourth waves of the community-representative, five-county, 10-year Duke Established Populations for Epidemiologic Studies of the Elderly study, carried out in a health service-rich area.

Participants

Cognitively intact survivors of the third wave (N = 1,740), who provided blood samples for standard laboratory work.

Measurements

Biomarkers (n = 28) were measured to develop a cumulative deficit laboratory test-based FI (Duke FI) derived from standard laboratory tests: SMAC-24 chemistry panel, high-density

SUBMITTER: King KE 

PROVIDER: S-EPMC5603383 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature