Metal exchange in lithiocuprates: implications for our understanding of structure and reactivity.

ABSTRACT: New reagents have been sought for directed ortho cupration in which the use of cyanide reagents is eliminated. CuOCN reacts with excess TMPLi (TMP = 2,2,6,6-tetramethylpiperidide) in the presence of limited donor solvent to give crystals that are best represented as (TMP)₂Cu_0.1Li_0.9(OCN)Li₂(THF) 8, whereby both Lipshutz-type lithiocuprate (TMP)₂Cu(OCN)Li₂(THF) 8a and trinuclear (TMP)₂(OCN)Li₃(THF) 8b are expressed. Treatment of a hydrocarbon solution of TMP₂CuLi 9a with LiOCN and THF gives pure 8a. Meanwhile, formation of 8b is systematized by reacting (TMPH₂)OCN 10 with TMPH and nBuLi to give (TMP)₂(OCN)Li

SUBMITTER: Peel AJ 

PROVIDER: S-EPMC5603898 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature