Percutaneous intratumoral injection of gemcitabine plus cisplatin mixed with fibrin glue for advanced pancreatic carcinoma: Case Report.

ABSTRACT:

Rationale

The aim of this study was to determine the effectiveness of intratumoral injection of chemotherapeutics in improving the quality of life and survival of patients with pancreatic carcinoma.

Patient concerns

We present a case series of 5 patients with unresectable pancreatic adenocarcinoma.

Diagnoses

Patients diagnosed with unresectable poorly differentiated pancreatic ductal adenocarcinoma by intraoperative frozen biopsyor percutaneous biopsy.

Interventions

Five patients with unresectable pancreatic adenocarcinoma received a computed tomography-guided percutaneous intratumoral injection of gemcitabine plus cisplatin mixed with fibrin glue.

Outcomes

Mean overall survival was 16.2 ± 3.7 months. Local control rates were 100% and 80% at postoperativ

SUBMITTER: Yang B 

PROVIDER: S-EPMC5604654 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature