Two passive mechanical conditions modulate power generation by the outer hair cells.

ABSTRACT: In the mammalian cochlea, small vibrations of the sensory epithelium are amplified due to active electro-mechanical feedback of the outer hair cells. The level of amplification is greater in the base than in the apex of the cochlea. Theoretical studies have used longitudinally varying active feedback properties to reproduce the location-dependent amplification. The active feedback force has been considered to be proportional to the basilar membrane displacement or velocity. An underlying assumption was that organ of Corti mechanics are governed by rigid body kinematics. However, recent progress in vibration measurement techniques reveals that organ of Corti mechanics are too complicated to be fully represented with rigid body kinematics. In this study, two components of the active feedback

SUBMITTER: Liu Y 

PROVIDER: S-EPMC5604991 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature